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Contemporary Philosopher, Alexander R. Pruss
In his blog, Parts and ownership, Alexander R. Pruss asserts that matter receives its identity from the substance that it makes up: “Therefore, no bit of matter can be a part of two substances. But everything that exists is a substance or a mode, relation, trope, accident or the like. A proper part of a…
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Aristotle’s hylomorphism
In Aristotle’s writing, Physics, he asserts every physical object is a compound of matter (hulê) and form (morphê, eidos), a theory known as hylomorphism. As one of the first writers during ancient times to introduce the concept of life scientifically, he believed that matter could exist without form, but form could not exist without matter. Therefore,…
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Asking the tough questions
The philosophy and ethics team are exploring the implications of the Indiana Center for Regenerative Medicine and Engineering’s post-mortem research findings and are developing approaches in the philosophy of biology that builds on these findings. Project investigators see this exploration as a powerful opportunity to advance regenerative medicine and philosophical understanding, by raising essential metaphysical…
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Meet our team
Chandan K. Sen, PhD, is distinguished professor and J. Stanley Battersby Chair of Surgery, Director of the Indiana Center for Regenerative Medicine and Engineering (ICRME), and executive director of the Comprehensive Wound Care Center at IU Methodist Hospital. At IU, he serves as associate vice president of research. At Indiana University Health, Dr. Sen is the executive…
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The research team will use three powerful technologies
These technologies will help us better understand which molecular pathways are responsible for mounting survival response in component tissues after organismal death.
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Why study skin?
Many genes are induced in organs, and the ICRME will focus on the skin, the largest organ of the body, for its post-mortem conatus research. Skin can live at a cellular level long after death and is a low energy consuming tissue that can harbor living cells longer than other parts of the body. Recent…
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Conatus
Conatus (Latin: to endeavor”) represents an innate ‘will to live’ of a thing, a striving to continue to exist and enhance itself. In modern-day biology, conatus describes autopoiesis – an inherent ability to self-regenerate. conatus by using advanced scientific technologies to study human cells while integrating philosophical discussions into our queries: DefinitionsHuman death is categorized…
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In human death, do organs and tissues mount a survival or regenerative response, despite a disconnection from the fate of the organism as a whole? If so, why?
This line of thinking emphasizes the following issues of broad significance:
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Core questions of Templeton Grant Research on Human Fetal Development Genes
Our quest for answers continues…